Evidence of presence of poliovirus genomic sequences in cerebrospinal fluid from patients with postpolio syndrome.

Normal serum levels of immune complexes in postpolio patients

OBJECTIVE The pathophysiology of the postpolio syndrome is not fully understood. Increased cytokine levels in cerebrospinal fluid and peripheral blood indicate a systemic inflammatory process. Decreased cytokine levels and the clinical effect of intravenous immunoglobulin treatment further indicate an inflammatory/immunological pathogenesis. The aim of the present study was to evaluate whether ...

Identification of Neisseria Meningitidis in Patients with Suspected Meningitis: a Study in Imam Reza Hospital, Kermanshah City, Iran, 2013

Background & Aims: Neisseria meningitidis is bacteria fastidious, and the main causes of meningitis and acute sepsis. Appropriate treatment depends on accurate and timely diagnosis. This study aimed to identify Neisseria meningitidis infection in samples of cerebrospinal fluid (CSF) in patients with suspected meningitis. Methods: In this study, 198 samples of cerebrospinal fluid of patients wit...

Cerebrospinal fluid nerve growth factor and total protein concentration in the children with meningitis

Meningitis is one of the most common infectious cerebral nervous system (CNS), defined as an inflammation of the meninges. It is clinically categorized into a chronic and acute based on the acuity of symptoms. Vomiting, bulging fontanel and fever are the main symptoms in the patients with meningitis. Bacterial meningitis is a severe, potentially life-threatening infection that is associated wit...

Genomic Analysis of Vaccine-Like Poliovirus Isolates from Stool Specimens of Acute Flaccid Paralysis Cases with Residual Paralysis during the Years 1380-1381 in Iran

Concentration of soluble form of hepatocyte growth factor receptor in cerebrospinal fluid and serum of patients with bacterial and viral meningitis

Abstract Background and objectives: C-Met is a proto-oncogene that encodes a protein known as hepatocyte growth factor receptor (HGFR). The HGF receptor possesses tyrosine -kinase activity and it is essential for embryonic development, wound healing and cancer. Many proteins are proteolytically released from the surface by a process known as ectodomain shedding. Shedding occurs under normal phy...